Research Journal of Pharmacognosy and Phytochemistry

G. B. Brindha Devi ¹, K. Amutha ²

Affiliations
1 Department of Biotechnology, School of Life Sciences, VELS University, Velan Nagar, Pallavaram, Chennai- 600 0117, Tamil Nadu, IN
2 Department of Biotechnology, School of Life Sciences, VELS University, Pallavaram, Chennai – 600117, IN

Abstract

Blumea mollis (Asteraceae) has been widely used in the traditional medicinal system for the treatment of a variety of diseases. However, to be clinically useful, more scientific data are needed. Therefore, in the present study, we investigated the effects of B. mollis on acute and chronic inflammation. To assess the anti-inflammatory and antipyretic activities, water extract of B. mollis was tested in carrageenan-induced rat paw oedema. The rat paw oedema is considered as one of the most useful laboratory tests for assessing the anti-inflammatory activity of potential herbal crude extracts. The paw volumes, pyrexia and writhes in experimental rats were reduced significantly (p < 0.05) as compared to that of control. The anti-inflammatory effect of B. mollis clearly illustrates that the extracts obtained with the whole plant parts produced statistically significant acute anti-inflammatory effects.

Keywords

Paw Oedema, Blume Mollis, Carageenan, Herbal Extracts.

Full Text

     

K. Amutha ¹, D. Victor Arokia Doss ¹

Affiliations
1 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, Tamil Nadu, IN

Abstract

Medicinal value of Barleria cristata is known traditionally in India. In the present study preliminary phytochemical screening, quantitative determination of secondary metabolites, vitamin content and in vitro antioxidant activity were carried out. Phytochemical screening revealed the presence of Phyto-chemicals such as alkaloids, flavonoids, glycosides, saponins, phenols and tannins in ethanol and aqueous extracts of Barleria cristata. The 50% ethanolic extract of leaves showed significant antioxidant activity which is due to the occurrence of secondary metabolites that can be used as antioxidant agents in future.

Keywords

Barleria cristata, Phytochemicals, in vitro Antioxidant Activity, Free Radical Scavenging Activity, Ash Value.

Full Text